CD20 is a membrane-embedded 33kDa nonglycosylated phosphoprotein which play a role in B-cell activation, differentiation, and cell-cycle progression. CD20 is a restricted B-cell antigen and its clinical utility is greatest for identifying B-lineage non-Hodgkin's lymphomas, but it can also aid in the diagnosis of nodular lymphocyte predominance Hodgkin's disease and acute lymphoblastic neoplasms.
Synthetic peptide corresponding to CD20 residues within aa197‐C terminal of CD20 was used as an immunogen.
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