CD35 Recombinant Rabbit Monoclonal Antibody

CD35, complement receptor 1, is a cell membrane-bound, monomeric glycoprotein on numerous cell types including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules.CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils, and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma.

Specifications

Catalog No.
BX50064
Clone No.
BP6069
Application
IHC-P
Subcellular location
Membrane
Control
Tonsil
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to CD35 residues within aa1939-2039 of CD35 was used as an immunogen.

Reference

1.Biddle DA et al. Mod Pathol. 2002 Jan;15(1):50-8.
2.Dogan A et al. Am J Surg Pathol. 2003 Jul;27(7):903-11.

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