Breast cancer
Thyroid cancer
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Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody
Cytokeratin 7 in humans is a proten encoded by the KRT7 gene. It is always as a keratin pair with Cytokeratin 19.Cytokeratin 7 is expressed on most ductal and glandular epithelium including lung, breast, bladder and female genital tract, but not in most gastrointestinal epithelium, prostate, hepatocyte and squamous epithelium. In tumor tissues, it expression is absent in colon cancer, prostate cancer and squamous carcinomas.Cytokeratin 7 is often used in concert with Cytokeratin 20 and CDX-2 to aid in distinguishing ovarian, pulmonary and breast carcinomas (CK7+) from colon carcinomas (CK7-).
Specifications
- Catalog No.
- BX50055
- Clone No.
- BP6060
- Application
- IHC-P
- Subcellular location
- Cytoplasm
- Control
- Breast cancer
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Synthetic peptide corresponding to Cytokeratin 7 residues within aa1-100 of Cytokeratin 7 was used as an immunogen.
Reference
1.Moll R, et al. Histochem Cell Biol. 2008 Jun;129(6):705-33.
2.Moll R, et al. Cell. 1982 Nov;31(1):11-24.
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