GCDFP-15 Recombinant Rabbit Monoclonal Antibody

GCDFP is a prolactin-induced, secretory, actin-binding cytoplasmic protein, also designated glycoprotein (gp). The cells within the body that produce GCDFP-15 appear to be restricted primarily to those with an apocrine function. It has been reported that cytosolic analysis of normal tissue from all major organs has demonstrated GCDFP15 in apocrine epithelia, lacrimal, ceruminous and Moll's glands and in numerous serous cells of the submandibular, tracheal, bronchial, sublingual and minor salivary glands. Cytosol from breast carcinoma lesions are reported to contain GCDFP15 at a wide range of concentrations. The concentration is reported to be highest in more differentiated carcinomas and GCDFP15 shows only a few positive individual epithelial cells within lobules and small ducts in normal breast. Expression has also been reported in fibroadenomas within areas of apocrine metaplasia.