Lymphoid Enhancing Factor 1 (LEF1) is a transcription factor that belongs to the TCF/LEF family.LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells.Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.
Specifications
Catalog No.
BX50108
Clone No.
BP6113
Application
IHC-P
Subcellular location
Nucleus
Control
Tonsil
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to residues within aa100-200 of LEF1 was used as an immunogen.
Reference
1.Ji Q et al. Nat Commun 10:313 (2019).
2.Przybyl J et al. Gynecol Oncol 149:388-393 (2018).