Human chorionic gonadotropin antibody (hCG) is a glycoprotein hormone synthesized in syncytiotrophoblastic cells of placenta and in certain trophoblastic tumors. The hormone-specific alpha chains have molecular weights of 13 kDa.HCG is found in moles and choriocarcinoma, chorionic components of germ cell tumours, and syncytiotrophoblast like cells in seminoma/dysgerminoma and embryonal carcinoma.In diagnostic pathology, hCG is a useful marker for classification of germ cell tumours, identification of extragonadal germ cell tumours.
Specifications
Catalog No.
BX50075
Clone No.
BP6080
Application
IHC-P
Subcellular location
Cytoplasm
Control
Placenta
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to residues within aa1-100 of hCG was used as an immunogen.
Reference
1.Losch A, Kainz C. Acta Obstet Gynecol Scand. 1996 Sep;75(8):753-6.
2.Kido A, Mori M, Adachi Y, Yukaya H, Ishida T, Sugimachi K. Surg Today. 1996;26(12):966-70.