PAX-5 Recombinant Rabbit Monoclonal Antibody

Pax genes are a family of developmental control genes that encode nuclear transcription factors and have been implicated in the control of mammalian development.

PAX-5 is a marker for B-cells, including B-lymphoblastic neoplasms and maturation stage. It is found in most cases of mature and precursor B-cell non-Hodgkin lymphomas/leukemias. In approximately 97% of cases of classic Hodgkin lymphoma, Reed-Sternberg cells express PAX-5.

The antibody is a useful tool for the identification of pro, pre, and mature B cells and for classification of lymphomas and subclassification of classic Hodgkin's lymphoma and anaplastic large cell lymphoma of the T and null-cell type.

Specifications

Catalog No.
BX50136
Clone No.
BP6140
Application
IHC-P
Subcellular location
Nucleus
Control
Tonsil
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to residues within aa300 to aa400 of PAX-5 was used as an immunogen.

Reference

1.Abdelrasoul H  et al. Sci Rep 8:1327 (2018).

2.Hijano DR  et al. Sci Rep 8:11034 (2018).

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