S100 Recombinant Rabbit Monoclonal Antibody

S100 is a 21kDa highly acidic and water soluble protein, which is expressed in a wide variety of normal and neoplastic cells of mesodermal, neuroectodermal, and epithelial origin. The protein is a dimer, having two subunits, alpha and beta, with extensive sequence homology. There are 3 forms of S-100 protein: alpha-alpha, known as S-100A0; alpha-beta, known as S-100A and beta-beta, known as S-100B. The immunohistochemical evaluation of S-100 (beta) protein expression is important in the diagnosis of undifferentiated malignant tumours of unknown primary origin and should be included in the so-called primary panel. S100 is a very sensitive marker for malignant melanoma of all types. S100 may be used in the differential diagnosis of sarcomas and spindle cell tumours.

Specifications

Catalog No.
BX50083
Clone No.
BP6088
Application
IHC-P
Subcellular location
Cytoplasm, Nuclears
Control
Melanoma
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to residues within aa50-150 of S100 was used as an immunogen.

Reference

1.Hagen EC, Vennegoor C, Schlingemann RO, Van der Velde EA, Ruiter DJ. Histopathol 1986;10:689-700.

2.Schafer BW, Heizmann CW. Trends Biochem Sci. 1996 Apr;21(4):134-40.

Support Documents

Order

  • E-mail : sales@biolynx.cn

Contact Us

Address
Hangzhou Bailing (Biolynx)  Biotechnology Co., Ltd. Room 1303 Bldg 5, #688 Bin’an Road Tianhe High-tech Park, Binjiang District Hangzhou, Zhejiang, China
310052
Phone & Fax
+86 571 88177680
+86 571 88177681
Web & Mail
Email:sales@biolynx.cn
www.biolynxtec.com

Follow Us

Scan QR Codes on Your Phone