PD-L1 Recombinant Rabbit Monoclonal Antibody

Programmed cell death ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a type 1 transmembrane protein involved in the regulation of cellular and humoral immune responses. The interaction of PD-L1 with its receptor PD-1 provides both stimulatory and inhibitory signals in regulating T cell activation and tolerance during pregnancy tissue allografts, autoimmune disease and malignant transformation.

Specifications

Catalog No.
BX00005
Clone No.
BP6001
Application
IHC-P
Subcellular location
Membrane
Control
Placenta
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Recombinant full length protein corresponding to Human PD-L1 (extracellular). The immunogen contains the specific extracellular domain of huPD-L1 (F19-T239).

Reference

1.Muenst S1, et al. Breast Cancer Res Treat. 2014 Jul;146(1):15-24. 
2.Lim SH, et al. Expert Opin Biol Ther. 2016;16(3):397-406. 

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