EGFR Recombinant Rabbit Monoclonal Antibody

EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3, -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head, neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Specifications

Catalog No.
BX50092
Clone No.
BP6097
Application
IHC-P
Subcellular location
Cytomembrane/Cytoplasma
Control
Lung Carcinoma  Tissue
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to EGFR residues within aa1050-1150 of EGFR was used as an immunogen.

Reference

1.Brustmann H, et al. Int J Gynecol Pathol. 2011 Jan; 30(1):76-83.

2.Vranic S, et al. Hum Pathol. 2010 Nov; 41(11):1617-23. 

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