CD14 Recombinant Rabbit Monoclonal Antibody

CD14 is receptor for endotoxin and apoptotic cells. It is expressed by monocytes/histiocytes, Langerhans' cells, follicular dendritic reticulum cells, neutrophils (weakly), and endothelial cells of the liver sinusoids.

CD14 is detected in myeloid leukaemias with monoblastic/monocytic differentiation, and in histiocytic neoplasms like histiocytic lymphoma, Langerhans' cell histiocytosis and giant cell tumour. In cultures, a subpopulation of Kaposi sarcoma cells express CD14.

In differential diagnosis, CD14 is more specific than CD68 in the identification of monocytes/histiocytes and associated neoplasias.

Specifications

Catalog No.
BX50106
Clone No.
BP6111
Application
IHC-P
Subcellular location
Membrane
Control
Appendix
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to residues within aa1-100 of Podoplanin was used as an immunogen.

Reference

1.Scott CS, Eur J Haematol. 1990 Jan;44(1):24-9.

2.Wright SD, Science 1990;249:1431-3.

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