CD2 is mainly present on the surface of mature T cells and NK cell membranes, while B cells are usually not expressed. It can be used to label the diagnosis and study of normal T cells and their associated tumors, such as pre-t cell lymphoma, marginal T cell lymphoma and anaplastic cell lymphoma. CD2 antibody is useful for identification of precursor and mature T-cell lymphomas. Aberrant loss of CD2 in T-cell lymphomas may help to distinguish them from reactive T-cell proliferations.
Specifications
Catalog No.
BX50102
Clone No.
BP6107
Application
IHC-P
Subcellular location
T cell lymphoma tissue
Control
Esophageal Carcinoma Tissue
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to residues within N-Term of CD2 was used as an immunogen.
Reference
1.Companioni Nápoles O, et al. J Gastroenterol 52:39-49 (2017).
2.DE Sanctis V, Belgioia L, et al. ANTICANCER RESEARCH 39: 1935-1942 (2019).