Tonsil
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c-Myc Recombinant Rabbit Monoclonal Antibody
Oncogene-encoded proteins c-Myc, n-Myc, and l-Myc function in cell proliferation, differentation and neoplastic disease. A mutated version of Myc is found in many cancers, which causes Myc to be constitutively expressed. This leads to the unregulated expression of many genes, some of which are involved in cell proliferation, and result in the formation of cancer. c-Myc is a transcription factor and is a proto-oncogene that is the focal point in cell cycle regulation, metabolism, apoptosis, differentiation, cell adhesion, and tumorigenesis.
Specifications
- Catalog No.
- BX50218
- Clone No.
- BP6195
- Application
- IHC-P
- Subcellular location
- Nucleus
- Control
- Tonsil
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Synthetic peptide residues in human c-Myc was used as an immunogen.
Reference
1. Hoff man B, et al. Oncogene. 2002; 21(21):3414-21.
2. Nakles R, et al. Mol Endocrinol. 2011; 25:549-63。
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