TROP-2 or Tumor-associated calcium signal transducer 2, also known as epithelial glycoprotein-1 antigen (EGP-1), is a protein that in humans is encoded by the TACSTD2 gene. This transmembrane glycoprotein functions in a variety of cell signaling pathways and was first elucidated as a transducer of an intracellular calcium signal.. TROP-2 is expressed in a variety of epithelial tissues and tumor tissues from which TROP2 originates, such as tonsil, esophagus, pancreatic, prostate and gastric cancers.
Specifications
Catalog No.
BX50231
Clone No.
BP6208
Application
IHC-P
Subcellular location
Membrane
Control
Thyroid
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide. This information is proprietary to Biolynx.
Reference
1. McDougall, A.R. et al. (2015) Dev Dyn 244, 99-109.
2. Shvartsur, A. and Bonavida, B. (2015) Genes Cancer 6, 84-105.