Cytokeratin 5 is a basic protein that is closely related to cytokeratin 6. They share similar tissue distribution and are found in various proportions in many non-keratinizing stratified squamous epithelia eg. tongue mucosa, as well as in basal epithelia of trachea, basal cells of epidermis, hair follicles, sebaceous and sweat glands of skin, luminal cells of the mammary gland, basal cells of prostate, urothelium, vagina and endocervical mucosa.
Specifications
Catalog No.
BX50144
Clone No.
BP6021/BP6065
Application
IHC-P
Subcellular location
Cytoplasm
Control
Lung squamous carcinoma
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide according to the aa490-590 (Cterminal) of cytokeratin 5 was used as an immunogen. Synthetic peptide corresponding to Cytokeratin 6 residues within aa464-564 of Cytokeratin 6 was used as an immunogen.
Reference
1. R Moll et al. Histochem Cell Biol (2008) 129:705–733.
2. R Moll et al. Cell, Vol. 31, 1 l-24, November 1982