Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
Specifications
Catalog No.
BX50141
Clone No.
1A4
Application
IHC-P
Subcellular location
Cytoplasm
Control
Prostate
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
N-terminal synthetic decapeptide of Human α-smooth muscle actin
Reference
1. Gabbiani G,et.al, Proc Natl Acad Sci U S A. 1981 Jan;78(1):298-302.
2. Itoga T, et.al,Pathol Int. 2003 Jun;53(6):371-5.