Forkhead box (Fox) proteins are a family of evolutionarily conserved transcription factors containing a sequence known as Forkhead box or winged helix DNA binding domain. The human genome contains 43 Fox proteins that are divided into subfamilies. The FoxP subfamily has four members, FoxP1 - FoxP4, which are broadly expressed and play important roles in organ development, immune response, and cancer pathogenesis. FoxP proteins usually function as transcriptional repressors.
Specifications
Catalog No.
BX50188
Clone No.
BP6166
Application
IHC-P
Subcellular location
Nucleus
Control
Colon cancer
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Recombinant fragment corresponding to human FOXP3 was used as an immunogen.
Reference
1. Zuo, T. et al. (2007) Cell 129, 1275-86.
2. Wang, L. et al. (2009) Cancer Cell 16, 336-46