Glypican 3, also known as GPC3, is a human gene. The protein encoded by this gene is a member of the glypican family. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl-phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
Specifications
Catalog No.
BX50251
Clone No.
BP6228
Application
IHC-P
Subcellular location
Cytoplasm
Control
Liver cancer
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to residues of Glypican-3 was used as an immunogen.
Reference
1. Anatelli F, et al. Am J Clin Pathol. 2008;130(2):219-23-8.
2. Kandil D, et al. Cancer. 2007;111(5):316-22.