PMEL 17（HMB-45） Recombinant Rabbit Monoclonal Antibody
PMEL 17 is a melanosome specific antigen, also is designed as HMB45 or gp100. It plays a central role in the biogenesis of melanosomes, involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures.
Specifications
- Catalog No.
- BX50026
- Clone No.
- BP6031
- Application
- IHC-P
- Subcellular location
- Cytoplasm
- Control
- Melanoma
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Synthetic peptide corresponding to PMEL 17 residues within aa561‐661 of PMEL 17 was used as an immunogen.
Reference
1.Rothberg BE, et.al, Mod Pathol. 2008 Sep;21(9):1121-9.
2.Wagner SN, et.al, Cancer Immunol Immunother. 1997 Jun;44(4):239-47.
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