MHC II (DR α chain) Recombinant Rabbit Monoclonal Antibody
Major histocompatibility complex class II (MHC class II) molecules are heterodimeric, transmembrane glycoproteins expressed on the surface of antigen-presenting cells such as macrophages, dendritic cells, and B cells. Expression can also be induced on other cell types through interferon-γ signaling. Prior to being displayed on the cell membrane, MHC class II molecules are loaded with exogenous peptide antigens approximately 15-24 amino acids in length that were derived from endocytosed extracellular proteins digested in the lysosome.
Specifications
Catalog No.
BX50192
Clone No.
BP6170
Application
IHC-P
Subcellular location
Membrane
Control
Tonsil
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide near N-terminal residues in Human MHC Ⅱ(DR α chain) was used as an immunogen.
Reference
1. Temponi, M. et al. J Immunol Methods 161 (1993) .
2. Ting, J.P. and Trowsdale, J. Cell 109 Suppl (2002).