PAX-5 Recombinant Rabbit Monoclonal Antibody
Pax genes are a family of developmental control genes that encode nuclear transcription factors and have been implicated in the control of mammalian development.
PAX-5 is a marker for B-cells, including B-lymphoblastic neoplasms and maturation stage. It is found in most cases of mature and precursor B-cell non-Hodgkin lymphomas/leukemias. In approximately 97% of cases of classic Hodgkin lymphoma, Reed-Sternberg cells express PAX-5.
The antibody is a useful tool for the identification of pro, pre, and mature B cells and for classification of lymphomas and subclassification of classic Hodgkin's lymphoma and anaplastic large cell lymphoma of the T and null-cell type.
PAX-5 is a marker for B-cells, including B-lymphoblastic neoplasms and maturation stage. It is found in most cases of mature and precursor B-cell non-Hodgkin lymphomas/leukemias. In approximately 97% of cases of classic Hodgkin lymphoma, Reed-Sternberg cells express PAX-5.
The antibody is a useful tool for the identification of pro, pre, and mature B cells and for classification of lymphomas and subclassification of classic Hodgkin's lymphoma and anaplastic large cell lymphoma of the T and null-cell type.
Specifications
- Catalog No.
- BX50136
- Clone No.
- BP6140
- Application
- IHC-P
- Subcellular location
- Nucleus
- Control
- Tonsil
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Synthetic peptide corresponding to residues within aa300 to aa400 of PAX-5 was used as an immunogen.
Reference
1.Abdelrasoul H et al. Sci Rep 8:1327 (2018).
2.Hijano DR et al. Sci Rep 8:11034 (2018).
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