Olig2 Recombinant Rabbit Monoclonal Antibody

Olig2, a basic helix–loop–helix transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. No Olig2 expression has been found in the non-glial tumors including neuroepithelial tumors, ependymomas, subependymomas, medulloblastomas, and nonneuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid/rhabdoid tumor, and haemangioblastomas.

Specifications

Catalog No.
BX50189
Clone No.
BP6167
Application
IHC-P
Subcellular location
Nucleus
Control
Oligodendroglioma
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to residues in Human Olig2 was used as an immunogen.

Reference

1.Shou JW et al. Front Cell Neurosci 13:395 (2019).
2. Cho KHT et al. Sci Rep 10:6904 (2020).

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