Brain
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Pan-TRK Recombinant Rabbit Monoclonal Antibody
pan-TRK, Full name of NTRK: Neurotrophic Receptor Kinase. NTRK gene includes three subtypes: NTRK1, NTRK2 and NTRK3, which are located on different chromosomes.The proteins encoded by NTRK are called TRK proteins, and NTRK1, NTRK2 and NTRK3 encode TRKA, TRKB and TRKC respectively.TRK protein is a type of receptor tyrosine kinase that contains the extracellular ligand-binding region, the transmembrane region, and the intracellular kinase region.When TRK binds to the ligand, dimerization occurs, and intracellular tyrosine kinase phosphorylation, signaling downstream.
Specifications
- Catalog No.
- BX50233
- Clone No.
- BP6210
- Application
- IHC-P
- Subcellular location
- Cytoplasm
- Control
- Brain
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Synthetic peptide corresponding to residues within aa350-450 of FOXP1 was used as an immunogen.
Reference
1. Brčić I, et al. Mod. Pathol. 2020 Aug 28.
2. Zhao M, et al. Histopathology 2020 Jun 26.
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