CD20 is a membrane-embedded 33kDa nonglycosylated phosphoprotein which play a role in B-cell activation, differentiation, and cell-cycle progression. CD20 is a restricted B-cell antigen and its clinical utility is greatest for identifying B-lineage non-Hodgkin's lymphomas, but it can also aid in the diagnosis of nodular lymphocyte predominance Hodgkin's disease and acute lymphoblastic neoplasms.
Specifications
Catalog No.
BX50002
Clone No.
BP6006
Application
IHC-P
Subcellular location
Membrane
Control
Tonsil
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to CD20 residues within aa197‐C terminal of CD20 was used as an immunogen.
Reference
1.N Johnson., et al. Blood 2009 113:3773-3780.
2.Clark EA., et al. Proc Natl Acad Sci U S A 1985;82:1766-1770.