The CD3 protein is a T-cell marker, a complex of four structurally distinct membrane glycoprotein isoforms, comprising extracellular, transmembrane and intracellular domains. The CD3 complex is responsible for mediating signal transduction to the internal environment upon antigenic recognition by TCR, causing T-cell proliferation and release of cytokines.
Specifications
Catalog No.
BX50022
Clone No.
BP6027
Application
IHC-P
Subcellular location
Membrane
Control
Tonsil
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to CD3E residues within aa1-100 of CD3E was used as an immunogen.