Desmin is a 53kDa intermediate filament (IF) protein that integrates the sarcolemma, Z disk, and nuclear membrane in sarcomeres and regulates sarcomere architecture. Desmin play no role in contractility but serves to maintain the orientation of actin and myosin filaments and may also play a role in nuclear transcription.
Specifications
Catalog No.
BX50139
Clone No.
D33
Application
IHC-P
Subcellular location
Cytoplasm
Control
Prostate
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Immunogen derived from human Leiomyoma.
Reference
1. Brodehl A., et al. Circ Cardiovasc Genet. 2013 Dec;6(6):615-23.
2. Colella R., et al. Am J Surg Pathol. 2010 Jan;34(1):10-7.