FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program.
FOXP1 is useful in subclassification of DLBCL and a high cutoff (≥80%) for FOXP1 is needed to achieve high specificity for the ABC subtype.
Specifications
Catalog No.
BX50107
Clone No.
BP6112
Application
IHC-P
Subcellular location
Tonsil
Control
Appendix
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to residues within aa350-450 of FOXP1 was used as an immunogen.
Reference
1.Rodenas-Cuadrado PM et al. J Comp Neurol 526:1235-1266.
2.Louis Sam Titus ASC et al. J Neurosci 37:6575-6587.