"MCM2 acts as component of the MCM2-7 complex, also plays a role in terminally differentiated hair cells development of the cochlea and induces cells apoptosis.MCM2 express in all proliferative cells.
As a special marker of cell proliferation, It is superior to Ki-67 in precancerous lesions of colon cancer, lung cancer and other epithelial tissues. It is helpful to study malignant mesothelioma and reactive mesothelioma."
Specifications
Catalog No.
BX50243
Clone No.
BP6220
Application
IHC-P
Subcellular location
Nucleus
Control
Tonsil
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Full length protein corresponding to Human MCM2.
Reference
1. Todorov I.T., Pepperkok R., Philipova R.N., Kearsey S.E.Cell Sci.107:253-265(1994).
2. Gao J., Wang Q., Dong C., Chen S., Qi Y., Liu Y.PLoS ONE10:E0133522-E0133534(2015).