Neuroblastoma
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NSE Recombinant Mouse Monoclonal Antibody
NSE is an intracytoplasmic protein, and enolase is a dimer in mammals. It has three subunits: 1, 2, and 3, which are mainly distributed in central nerve, peripheral nerve, neuroendocrine cells and tumor cells.This antibody can specifically recognize 47kDa of NSE, and can be used for the auxiliary diagnosis of neuroendocrine tumors. Due to the poor specificity of the antibody, some normal smooth muscle, myoepithelial cells, renal tubular cells, lymphocytes can also express NSE. Therefore, this antibody is not used as a single diagnostic marker, and should be applied in combination with other indicators to improve its diagnostic accuracy.
Specifications
- Catalog No.
- BX50169
- Clone No.
- BPM6150
- Application
- IHC-P
- Subcellular location
- Cytoplasm
- Control
- Neuroblastoma
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Synthetic peptide within Human NSE aa 416-433.
Reference
1. Thrivikraman G et al. Nat Commun 10:3520 (2019).
2. Foucar, K et al. Int J Lab Hematol. 2020;00:1–5.
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