Placenta
Gastric denocarcinoma
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S100P Recombinant Rabbit Monoclonal Antibody
S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa , but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes.S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.
Specifications
- Catalog No.
- BX50013
- Clone No.
- BP6018
- Application
- IHC-P
- Subcellular location
- Cytoplasma/Nucleus
- Control
- Placenta
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Synthetic peptide according to the C-terminus of S100P was used as an immunogen.
Reference
1.Jiang H et.al. J Cancer Res Clin Oncol. 2012 Jan;138(1):1-9.
2.Seppo Parkkila et.al. BMC Clin Pathol. 2008; 8: 2.
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