Tonsil
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SMAD4 Recombinant Rabbit Monoclonal Antibody
SMAD 4 Plays a central role in the balance between atrophy and hypertrophy, also acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. It's a component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling and promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA.
Specifications
- Catalog No.
- BX50242
- Clone No.
- BP6219
- Application
- IHC-P
- Subcellular location
- Cytoplasm, Nuclears
- Control
- Tonsil
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Full length protein corresponding to Human SMAD 4.
Reference
1. iu F., Pouponnot C., Massague J.Genes Dev. 11:3157-3167(1997)
2. Seong H.A., Jung H., Kim K.T., Ha H.J. Biol. Chem.282:12272-12289(2007).
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