TLE1 Recombinant Rabbit Monoclonal Antibody
TLE1 binds to a number of transcription factors. It inhibits NF-kappa-B-regulated gene expression,also inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. It enhances FOXG1/BF-1- and HES1-mediated transcriptional repression. TLE1 is wildly expressed in normal and cancer tissues. TLE1 is generally use for diagnosis of synovial sarcoma.
Specifications
- Catalog No.
- BX50246
- Clone No.
- BP6223
- Application
- IHC-P
- Subcellular location
- Nucleus
- Control
- Synovial sarcoma
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Full length protein corresponding to Human TLE1.
Reference
1. Tetsuka T., Uranishi H., Imai H., Ono T., Sonta S. J. Biol. Chem. 275:4383-4390(2000).
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