Prostate cancer
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AMACR Recombinant Mouse Monoclonal Antibody
AMACR (P504S protein, 48 kDa) plays a role in the beta-oxidation of branched-chain fatty acids and their derivatives. AMACR is found in mitochondria and peroxisomes of numerous tissues such as prostate, liver, biliary tract, kidney and lung. Using immunohistochemistry, non-neoplastic prostate show a weak or focal staining reaction in about 20% of the cases. The reactivity tends to decrease with age but the correlation coefficient is low. AMACR antibody is mainly used in clinical diagnosis of prostate cancer.
Specifications
- Catalog No.
- BX50250
- Clone No.
- BPM6227
- Application
- IHC-P
- Subcellular location
- Cytoplasm
- Control
- Prostate cancer
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Synthetic peptide corresponding to residues of AMACR was used as an immunogen.
Reference
1. Marx, A. et al. (2008) Virchows Arch 453, 243-248.
2. Li, W. et al. (2008) J Exp Clin Cancer Res 27, 2.
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