Appendix
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MUC2 Recombinant Mouse Monoclonal Antibody
Mucin 2 glycoprotein (MUC2) is a 540 kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC2 is a mucus-forming secreted mucin found in the cytoplasm of goblet cells in small intestine, colon, bronchus and salivary glands. MUC2 expression has been noted in primary gastrointestinal tract tumors of colonic, gastric and esophageal origin. MUC2 expression has also been found in goblet cells in colorectal carcinoma metastatic to the ovary, but not in primary mucinous ovarian adenocarcinoma.
Specifications
- Catalog No.
- BX50172
- Clone No.
- CCP58
- Application
- IHC-P
- Subcellular location
- Cytoplasm
- Control
- Appendix
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- A 29 amino acids synthetic peptide (MI-29) containing one repeat unit of 23 amino acids and part of the next repeat of four amino acids in the VNTR (variable number of tandem repeats).
Reference
1. Chaves P, et al. Dis Esophagus. 2005; 18:383-7.
2. Mino-Kenudson M, et al. Arch Pathol Lab Med. 2007; 131:86-90.
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