Myeloid differentiation factor 88 (MYD88), a primary differentiation response gene in Myeloid precursors, was discovered in 1990s. MYD88 is a universal connexin containing three main structures: N-terminal death domain (DD), intermediate connexin domain (ID), and C-terminal Toll/ interleukin-1 receptor domain (TIR). After ligand binding, the cytoplasmic TIR domain of toll-like receptor (TLR) or IL1R binds to TIR of MYD88.
Specifications
Catalog No.
BX50265
Clone No.
BP6242
Application
IHC-P
Subcellular location
Cytoplasm
Control
293T cell MYD88 L265P
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide. This information is proprietary to Biolynx.
Reference
1. Vu N. Ngo, et al. Nature. 2011 February 3; 470(7332): 115–119.
2. Xose S. Puente, et al. Nature. 2011 JULY 7; 475: 110–115.