PAX-8 Recombinant Rabbit Monoclonal Antibody

PAX-8 is a transcription factor expressed during embryonic development of Müllerian organs, kidney, and thyroid, with continued expression in some epithelial cell types of these mature tissues. It can be useful for marking several types of carcinoma including ovarian serous carcinoma, clear cell renal cell carcinoma, and papillary thyroid carcinoma. Additionally, PAX-8 is not found in the epithelial cells of the breast, lung, mesothelium, stomach, colon, pancreas and other sites.

Specifications

Catalog No.
BX50179
Clone No.
BP6157
Application
IHC-P
Subcellular location
Nucleus
Control
Thyroid
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to PAX-8 was used as an immunogen. The exact sequence is proprietary.

Reference

1. Hsu CF et al. EBioMedicine 41:597-609 (2019).
2. Drusian L et al. Cell Rep 24:1093-1104.e6 (2018).

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