CD56, also known as neural cell adhesion molecule (NCAM), is a calcium-independent homophilic binding protein that belongs to a group of cell adhesion molecules including cadherins, selectins, and integrins. CD56 is involved in cell–cell adhesion of neural cells during embryogenesis and is expressed on most neuroectodermally derived tissues. In normal tissue, anti-CD56 labels neurons, glia, schwann cells, NK (natural killer) cells, and a subset of T-cells. CD56 expression can be seen in most NK cell neoplasms, certain subtypes of T-cell lymphoma and in some plasma cell neoplasms.
Specifications
Catalog No.
BX50178
Clone No.
BP6156
Application
IHC-P
Subcellular location
Membrane
Control
Brain
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide within Human NCAM1
Reference
1. Thoulouze M.I., et al. J. Virol. 72:7181-7190(1998).
2. Feng Q et al. et al. J Cell Physiol 234:6561-6581 (2019).