Growth hormone (GH), somatotropin, is the primary hormone responsible for regulating overall body growth and is also important in organic metabolism. It is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. GH stimulates growth indirectly by promoting the liver's production of somatomedins, which act directly on bone and soft tissue to cause growth. GH exerts direct metabolic effects on the liver, adipose tissue and muscle. In general, growth hormone enhances protein synthesis, conserves carbohydrates and uses up fat stores.
Specifications
Catalog No.
BX50213
Clone No.
BPM6190
Application
IHC-P
Subcellular location
Cytoplasm
Control
Prepituitary gland
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to Human Growth Hormone protein was used as an immunogen. The exact sequence is proprietary.
Reference
1. Sun H et al. Nat Commun 7:10339 (2016).
2. Kunert R et al. Appl Microbiol Biotechnol 84:693-9 (2009).