PD-L1 Recombinant Rabbit Monoclonal Antibody
Programmed cell death ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a type 1 transmembrane protein involved in the regulation of cellular and humoral immune responses. The interaction of PD-L1 with its receptor PD-1 provides both stimulatory and inhibitory signals in regulating T cell activation and tolerance during pregnancy tissue allografts, autoimmune disease and malignant transformation.
Specifications
- Catalog No.
- BX50137
- Clone No.
- BP6141
- Application
- IHC-P
- Subcellular location
- Membrane
- Control
- Lung cancer
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Recombinant full length protein corresponding to Human PD-L1 (extracellular). The immunogen contains the specific extracellular domain of huPD-L1 (F19- T239).
Reference
1. Muenst S1, et al. Breast Cancer Res Treat. 2014 Jul;146(1):15-24.
2. Lim SH, et al. Expert Opin Biol Ther. 2016;16(3):397-406
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